HORDB

ID: hor005846
Uniprot ID: Q17093
Protein name: LWamide I
Gene name: NA
Organism: Anemonia sulcata (Mediterranean snakelocks sea anemone)
Family: LWamide neuropeptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Anemonia (genus), Actiniidae (family), Actiniaria (order), Hexacorallia (subclass), Anthozoa (class), Cnidaria (phylum), Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QAGLW
Length: 5(16-20)
Propeptide: KRQQPGLWGRSADPQQAGLWGKRQQPGLWGRSADPQQAGLWGKRQNPGLWGRSADPQQAGLWGKRQHPGLWGRSADPQQAGLWGRSAGSGKRQERIGIWGRSAEPPQYKELEDLKQKSAIPKAKPQ
Signal peptide: NA
Modification: T5 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Function: Metamorphosin A may be part of an internal signaling system involved in control of metamorphosis.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005846_AF2.pdb

hor005846_ESM.pdb

Mass:	64519	Formula:	C27H39N7O7
Absent amino acids:	CDEFHIKMNPRSTVY	Common amino acids:	AGLQW
pI:	6.11	Basic residues:	0
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	16	Boman Index:	446
Half-Life / Aliphatic Index:	0.8 hour	Aliphatic Index:	98
Instability Index:	5536	Extinction Coefficient cystines:	5500
Absorbance 280nm:	1375